Numerous new clinical observations illustrate the importance of histology to clinical practice. More than 170 photomicrographs as well as new drawings, and histology laboratory instructions in most chapters have been added to this edition. Greatly revised content includes new findings in cellular and molecular biology such as the newly discovered endoplasmic reticulum-shaping proteins, the abundance of stem cells in adipose tissue, the phases of Alzheimer s disease and the role of the newly discovered glymphatic system in slowing the progression of the disease, and developments in the microbiome. More quick-reference tables have been added to summarize information discussed in the text. PowerPoint presentations, bolded key terms, bulleted lists, and chapter summaries highlight.