This gold-standard practical guide and reference to the safe and effective use of the latest antidepressant medications comprehensively explains in detail the welter of therapeutic options available to frontline physicians who prescribe antidepressants. Single-mindedly concentrating on information of high relevance to their daily clinical use, the authors review the latest developments concerning these medications and demonstrate how experts in the field approach the treatment of depression. Their clinical recommendations cover a wide range of uses in special populations, including geriatric depression, bipolar depression, psychotic depression, substance abuse and depression, HIV/AIDS-related depression, depression associated with pregnancy, post-traumatic stressdisorder, and depression in children.