Medical surgical nursing is a major subject to be studied in any basic nursing curriculum prescribed by Indian Nursing Council. Knowledge of this subject paves way in learning other branches of Nursing. Number of books with multiple volumes have been written on this subject. In our experience, we have found that students get lost in those volumes of books. This book has been presented in a simple, comprehensive, pointwise and student-friendly manner. The style of presentation would not only make it easy for students to understand the subject in a better manner but would also help them to quickly review and revise the subject before examination. This book also has been written by keeping in mind the need of the students to know in detail about the nursing management of patient with systemwise various disease conditions. If the students gain this nursing knowledge, It can be utilized in taking care of individual patient in health care settings. Further to make learning simple and interesting, tables, flow charts, diagrams have been included.